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Author Guidelines

General guidelines

Audience

The audience for Clinical Management Issues consists of clinicians, both general practitioners and specialists, especially internists. Authors should bear in mind the multidisciplinary status of the readership when writing the article.

Key formatting points

Please ensure your paper concurs with the following article format:

  • Title: concise, preferably not more than 180 characters.
  • Author(s) names, affiliations, and email.
  • Corresponding author: including full name and e-mail. Address, phone and fax numbers may also be reported.
  • Type of article: case report, article on clinical management, editorials, case series, congress report, retrospective analysis, applied research, or clinical trial
  • Abstract: about 600-1,000 characters. No references should be cited in the abstract
  • Keywords: approximately 3-5 keywords, preferably taken from the Mesh Terms (PubMed)
  • Body of the article: article content under relevant headings and subheadings; according to the type of article, different sections are required (see below). For case reports, authors should follow the CARE Guidelines
  • Diagnostic-therapeutic algorithm (optional, but highly suggested): tree-shaped, based on updated guidelines
  • The recommendations, or the most common errors, or the myths to be busted, or the traps to be avoided or the key points: a short summary in a bullet list
  • References (For full details on formatting see “Manuscript preparation” section below):
  1. Should be numerically listed in the reference section in the order that they occur in the text or in Tables and Figures
  2. Should appear as a number i.e., [1,2] in the text
  3. Quote first three authors’ names. If there are more than three, then quote first three, et al.
  • Figures/Tables (For full details on formatting see “Manuscript preparation” section below): summary figures/tables/boxes are very useful, and we encourage their use in articles. The author should include illustrations and tables to condense and illustrate the information they wish to convey. Commentary that augments an article and could be viewed as “stand-alone” should be included in a separate box. An example would be a summary of a particular trial or trial series, a case study summary or a series of terms explained. If any of the figures or tables used in the manuscript requires permission from the original publisher, it is the author’s responsibility to obtain this. Figures must be in an editable format.

Type of articles

Case reports

A case report may be of interest to readership of Clinical Management Issues when:

  • It concerns the decision-making process related to examination, evaluation, and diagnosis, for example, the presentation of an unusual combination of conditions, events or symptoms that may complicate the diagnosis or cast doubt on the choice of the treatment;
  • It allows the description of new side effects of drugs, or interactions never observed before;
  • It allows the study of the mechanism of a not well-known disease, or the detection of rare manifestations of a disease;
  • It explains a new method, both of diagnosis or analysis;
  • It highlights misdiagnoses involving severe risks for the patients;
  • It has educational purposes, favoring, through the presentation of a real case, the review or the learning of diagnostic processes and the knowledge related to a given disease;
  • It describes a deficiency in the therapeutic efficacy of a given intervention.

Word count: not less than 1800 words (excluding abstract and references)

Required sections

Authors are encouraged to follow the CARE Guidelines and to use the Checklist CARE in order to ensure that all relevant data of the clinical case has been reported. The CARE guidelines also provide a useful “Case report writing template for authors”.

Please note that the following sections recommended by the CARE Guidelines should be included under the section “Case Presentation”: Patient Information, Clinical Findings, Timeline, Diagnostic Assessment, Therapeutic Intervention, Follow-up and Outcomes. 

  • Abstract
  • Keywords
  • Introduction
  • Case Presentation:
    • Patient Information
    • Clinical Findings
    • Timeline
    • Diagnostic Assessment
    • Therapeutic Intervention
    • Follow-up and Outcomes
  • Discussion
  • Conclusion
  • Box "Why we describe this case": describing the main interests of the case report (50-70 words)
  • Box "What should the clinician ask him/herself or the patient?" (optional, but highly suggested): reporting the questions that should be asked facing such a patient (50-70 words)
  • Diagnostic-therapeutic algorithm (optional, but highly suggested)
  • Box "The recommendations", or "The most common errors", or "The myths to be busted", or "The traps to be avoided" or "The key points": a short summary in a bullet list
  • References (for full details on formatting see “Manuscript preparation” section below)
  • Disclosure/Acknowledgments

Information on the identity of patients (text or images) should not be published, unless they are essential for the scientific purposes of the article. In this case, authors should require written consent from patients: the document should be at SEEd’s disposal. The Consent Request form should be asked to the editorial staff (l.fasciopecetto@edizioniseed.it)

Articles on clinical management

Articles on clinical management generally give an overview on the management of a specific pathology or a group of diseases, focusing on the differential diagnoses and/or the possible treatments. The information given should be updated according to the most recent guidelines.

Word count: not less than 2500 words (excluding abstract and references)

Required sections

  • Abstract
  • Keywords
  • Introduction
  • Issue Description
  • Diagnosis (if relevant)
  • Treatment (if relevant)
  • Discussion
  • Conclusion
  • Diagnostic-therapeutic algorithm (optional, but highly suggested)
  • Box "The recommendations", or "The most common errors", or "The myths to be busted", or "The traps to be avoided" or "The key points": a short summary in a bullet list
  • References (For full details on formatting see “Manuscript preparation” section below)
  • Disclosure/Acknowledgments
Editorials

Editorials are short articles on issues of topical importance. We encourage our editorial writers to express their opinions, giving the author the opportunity to present criticism or address controversy. The intention is very much that the article should offer a personal perspective on a topic of recent interest.

Figures and tables can be included in editorials, if necessary.

Abstract: not needed

Word count: not less than 800 words

Case series

The case series describes the clinical course of a disease in a limited patient sample with similar diagnoses or undergoing the same procedure.

Word count: not less than 2500 words (excluding abstract and references)

Required sections

  • Abstract
  • Keywords
  • Introduction
  • Case Series Study Design:
      • Question
      • Study Population
      • Intervention
      • Outcome Measures
      • Statistical Analysis
  • Results
  • Discussion
  • Conclusion
  • A table reporting the main data for each patient (basal conditions and results)
  • Box "The recommendations", or "The most common errors", or "The myths to be busted", or "The traps to be avoided" or "The key points": a short summary in a bullet list
  • References (For full details on formatting see “Manuscript preparation” section below)
  • Disclosure/Acknowledgments 
Brief report

Brief Reports include small-scale research, preliminary results or pilot study addressed to a discrete research question. Scientific rigor and formal accuracy must be guaranteed. Brief reports should bring out a message adequate for the journal’s scope and of particular interest to the community.

Word count: not less than 2000 words

Required sections: the structure of the article is free, depending on the type of research and results.

Retrospective analysis

The retrospective analysis is a non-interventional study describing the data about patients’ exposures to suspected risk or protection factors in relation to an outcome that is established at the beginning of the study.

Word countabout 5000 words (references included)

Required sections (for a more detailed description of these sections see “Manuscript preparation” section):

  • Abstract
  • Keywords
  • Patients and methods
  • Results, including basal data and data after the observation period
  • Discussion
  • Box "The recommendations", or "The most common errors", or "The myths to be busted", or "The traps to be avoided" or "The key points": a short summary in a bullet list
  • References (For full details on formatting see “Manuscript preparation” section below)
  • Disclosure/Acknowledgments

Every retrospective analysis submitted to CMI should include a statement that the study obtained ethics approval by the ethical committee (or a simple acknowledgment , or a statement that it was not required), reporting also the name of the ethics committee and the ID.

Clinical trial

The clinical trial is an interventional study investigating about the outcomes generated by biomedical interventions.

Word count: approximately 5000 (references included)

Required sections (for a more detailed description of these sections see “Manuscript preparation” section):

  • Abstract
  • Keywords
  • Patients and methods
  • Results, including basal data and data after the intervention
  • Discussion
  • Box "The recommendations", or "The most common errors", or "The myths to be busted", or "The traps to be avoided" or "The key points": a short summary in a bullet list
  • References (For full details on formatting see “Manuscript preparation” section below)
  • Disclosure/Acknowledgments

Every clinical trial submitted to CMI should include a statement that the study obtained ethics approval by the ethical committee (or a simple acknowledgment , or a statement that it was not required), reporting also the name of the ethics committee and the ID, and a statement that participants gave informed consent before taking part.

For articles concerning research on human beings, Authors should also provide assurance that the study protocol conformed to the 1975 Declaration of Helsinki.

For studies involving animal experimentation, Authors should provide assurance that all animals received humane care according to the criteria described in the "Guide for the Care and Use of Laboratory Animals" published by the National Institutes of Health and available at https://grants.nih.gov/grants/olaw/Guide-for-the-Care-and-use-of-laboratory-animals.pdf.

Applied research

Articles on applied research generally describe experimental in vitro studies on the effect of drugs or combinations of drugs on a particular setting reproducing somehow the physiological conditions.

Word count: approximately 5000 (references included)

Required sections (for a more detailed description of these sections see “Manuscript preparation” section):

  • Abstract
  • Keywords
  • Key points including “Unmet need”, “Drugs studied”, and “Innovative aspects”
  • In vitro tests: an overview (optional)
  • References (For full details on formatting see “Manuscript preparation” section below)
  • Disclosure/Acknowledgment
Congress report

The congress report is an article describing the speech given by an author during an official meeting.

Word  count: not indicated

Required sections: the structure of the article is free, depending on the type and the length of the speech.

Manuscript preparation

Spacing and headings

Please use double line spacing throughout the manuscript. No more than three levels of subheading should be used to divide the text and should be clearly designated.

Abbreviations

Abbreviations should be defined on their first appearance, and in any table and figure footnotes. It is helpful if a separate list is provided of any abbreviations.

Language

The submitted manuscripts may be written in Italian or in English (preferable). Please use U.S. English spelling.

SEEd offers a service for authors who are not native English. Please contact us if you need any language service, as English language editing or translation.

References Format
  • Author’s names should appear without full stops in their initials
  • Quote first three authors’ names. If there are more than three, then quote first three, et al
  • Journal name should be in italics and abbreviated to standard PubMed format
  • Volume number followed by colon, not bold
  • Page number range separated by a hyphen with no spaces
  • DOI numbers
References Examples
  • Journal example: Hostler D, Everson-Stewart S, Rea TD, et al; Resuscitation Outcomes Consortium Investigators. Effect of real-time feedback during cardiopulmonary resuscitation outside hospital: prospective, cluster-randomised trial. BMJ 2011; 342: d512; http://dx.doi.org/ 10.1136/bmj.d512
    or: Houssami N, Abraham LA, Miglioretti DL, et al. Accuracy and outcomes of screening mammography in women with a personal history of early-stage breast cancer. JAMA 2011; 305: 790-9; http://dx.doi.org/ 10.1001/jama.2011.188
  • Book example: Lunet N. Meta-analysis of observational studies. In: La Torre G (ed). Applied Epidemiology and Biostatistics. Torino: SEEd Medical Publishers, 2010
  • Meeting abstract example: Smith AB, Jones CD. Recent progress in the pharmacotherapy of diseases of the lower urinary tract. Presented at: 13th International Symposium on Medicinal Chemistry. Atlanta, GA, USA, 28 November-2 December 1994
  • Website example: Merriam-Webster’s Collegiate Dictionary. 11th ed. Springfield, MA: Merriam-Webster Inc, 2003. Available at: http://ww.m-w.com/dictionary.htm (last accessed November 2012)
    or: National Institute for Health and Clinical Excellence. Antisocial personality disorder. London: NICE, 2009. Available at: http://guidance.nice.org.uk/CG77/PublicInfo/pdf/English (last accessed October 2012)
Figures and schemes

Figures should be numbered consecutively according to the order in which they have been first cited in the text. Define in the legend all abbreviations that are used in the figure.

Figures should be provided in separate files to the text. Please submit any Figure in .tiff or .jpg format. Photos should be provided at a resolution of 300 dpi, or as high as possible.

Schemes, diagrams and flow-charts should be provided in an editable electronic format such as PowerPoint, or Excel.

Tables and boxes

Tables should be numbered consecutively according to the order in which they have been first cited in the text. Define in the legend all abbreviations that are used in the table/box. Tables and boxes can be incorporated into the body of the manuscript, preferably in either Word or Excel format.

Tables and Figures Copyright

If a table, or a figure or a box has been published previously (even if you were the author), acknowledge the original source and submit written permission from the copyright holder to reproduce the material where necessary.

As the author of your manuscript, you are responsible for obtaining permissions to use material owned by others. Since the permission-seeking process can be remarkably time-consuming, it is wise to begin writing for permission as soon as possible.

Please send us photocopies of letters or forms granting you permission for the use of copyrighted material so that we can see that any special requirements with regard to wording and placement of credits are fulfilled. Keep the originals for your files. If payment is required for use of the table/box, this should be covered by the author.

 

Submission Preparation Checklist

As part of the submission process, authors are required to check off their submission's compliance with all of the following items, and submissions may be returned to authors that do not adhere to these guidelines.

  1. The submission has not been previously published, nor is it before another journal for consideration (or an explanation has been provided in Comments to the Editor).

  2. The submission file is in OpenOffice, Microsoft Word, RTF, or WordPerfect document file format.

  3. Where available, DOI and URLs for the references have been provided.

  4. The text is single-spaced; uses a 12-point font; employs italics for foreign phrases, and bold for emphasis rather than underlining (except with URL addresses); and all illustrations, figures, and tables are placed within the text at the appropriate points, rather than at the end.

  5. The text adheres to the stylistic and bibliographic requirements outlined in the Author Guidelines, which is found in About the Journal.
  6. If submitting to a peer-reviewed section of the journal, the instructions in Ensuring a Blind Review have been followed.
  7. The Authors will also sign and send to the Publisher the International Committee of Medical Journal Editors (ICMJE) form for Disclosure of Potential Conflicts of Interest (downloadable here)

 

Copyright Notice

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution Non-Commercial 4.0 Licence that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
    2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal. The Publication Agreement can be downloaded here, and should be signed by the Authors and sent to the Publisher when the article has been accepted for publication in this journal.
    3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
    4. Authors are permitted to post their work online after publication (the article must link to publisher version, in html format)

 

Privacy Statement

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